The islet's bridesmaid becomes the bride: Proglucagon-derived peptides deliver transformative therapies.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33831374.
- Also identified by DOI 10.1016/j.cell.2021.03.019.
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Abstract
The 2021 Gairdner Prize is awarded to Daniel Drucker, Joel Habener, and Jens Juul Holst for the discovery of novel peptides encoded in the proglucagon sequence and the establishment of their physiological roles. These discoveries underpinned the development of therapeutics that are now benefiting patients with type 2 diabetes and other disorders worldwide.
Medical subject headings
- Diabetes Mellitus, Type 2
- Glucagon-Like Peptide 1
- Glucagon-Like Peptide 2
- Proglucagon