Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 33857302.
- Also identified by DOI 10.1093/infdis/jiab209 and PMC identifier 9113508.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns <32 weeks gestation. Molecular and microscopic methods were used for detection of P. jirovecii in patients' specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of 56 newborns and in 7 oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Compared to noncolonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized infants (P = .02), suggesting a potential clinical importance of this pathogen in abnormal lung development.
Medical subject headings
- Pneumocystis
- Pneumocystis carinii
- Pneumonia, Pneumocystis
- Respiratory Distress Syndrome