Response to Comment on "Circadian rhythms in the absence of the clock gene <i>Bmal1</i>".

Ray, Sandipan; Valekunja, Utham K; Stangherlin, Alessandra; Howell, Steven A; Snijders, Ambrosius P; Damodaran, Gopinath; Reddy, Akhilesh B · Science · 2021

Where this comes from

Abstract

Ness-Cohn <i>et al</i> claim that our observations of transcriptional circadian rhythms in the absence of the core clock gene <i>Bmal1</i> in mouse skin fibroblast cells are supported by inadequate evidence. They claim that they were unable to reproduce some of the original findings with their reanalysis. We disagree with their analyses and outlook.

Medical subject headings