Founder cells shape brain evolution.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 33861961.
- Also identified by DOI 10.1016/j.cell.2021.03.045.
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Abstract
Humans have an extraordinarily expanded and complex cerebral cortex, relative to non-human primates. Yet the mechanisms underlying cortical differences across evolution are unclear. A new study by Benito-Kwiecinski et al. employs cerebral organoids derived across great apes to implicate neuroepithelial progenitor shape transitions in human cortical expansion.
Medical subject headings
- Hominidae
- Organoids