Characteristics and Outcomes of Children With Cystic Fibrosis Hospitalized With Cirrhosis in the United States.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 33927124.
- Also identified by DOI 10.14309/ajg.0000000000001275 and PMC identifier 8484050.
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Abstract
To describe the characteristics and outcomes of children with cystic fibrosis (CF) hospitalized with cirrhosis in the United States. We conducted a population-based cohort study of hospitalizations among children with CF using the 2016 Kid's Inpatient Database. In total, 9,615 admissions were analyzed. Diagnosis of cirrhosis was present in 509 (5.3%) and was significantly associated with increased mortality, length of stay, and hospital charges compared with those without cirrhosis. Hepatic encephalopathy was significantly associated with death in children with cirrhosis. Future interventions should be designed to support children with CF who have cirrhosis to improve clinical outcomes.
Medical subject headings
- Cystic Fibrosis
- Hospitalization
- Liver Cirrhosis