International Trends in Esophageal Squamous Cell Carcinoma and Adenocarcinoma Incidence.

Rumgay, Harriet; Arnold, Melina; Laversanne, Mathieu; Whiteman, David C; Thrift, Aaron P; Wei, Wenqiang; Lemmens, Valery E P P; Soerjomataram, Isabelle · Am J Gastroenterol · 2021

cross_sectional · Level IV

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Abstract

We aimed to improve our understanding of the epidemiology of squamous cell carcinoma and adenocarcinoma of the esophagus. We estimated average annual percent change and analyzed age-period-cohort trends on population-based cancer data. We found decreases in squamous cell carcinoma incidence in half of male populations (largest decrease in US black males [average annual percent change -7.6]) and increases in adenocarcinoma incidence in nearly a third of populations. Trends may be associated with a mix of birth cohort and period effects. More complete data and evidence are needed to conclude the reasons for the observed trends (see Visual Abstract, Supplementary Digital Content 4, http://links.lww.com/AJG/B823).

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