The imitation game: How glioblastoma outmaneuvers immune attack.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33930294.
- Also identified by DOI 10.1016/j.cell.2021.04.008.
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Abstract
Immune evasion and resistance to immunotherapy mark major roadblocks in treating glioblastoma, the deadliest form of brain cancer. In this issue of Cell, Gangoso et al. demonstrate that the immune microenvironment drives glioblastoma cells to hijack myeloid-characteristic transcriptional and epigenetic circuits as a mode of immune evasion.
Medical subject headings
- Brain Neoplasms
- Glioblastoma