Measuring the size and decay dynamics of the HIV-1 latent reservoir.

Liu, Runxia; Catalano, Allison A; Ho, Ya-Chi · Cell Rep Med · 2021

basic_science · Level V

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Abstract

Measuring HIV-1 latent reservoir is essential for HIV-1 cure strategies. Levy et al.<sup>1</sup> developed a multiplex droplet digital PCR (ddPCR) assay-5-target intact proviral DNA assay-to detect multiple regions of HIV-1 proviral genome and increase accuracy.

Medical subject headings