Too much of a good thing: Excess exercise can harm mitochondria.

Pataky, Mark W; Nair, K Sreekumaran · Cell Metab · 2021

editorial · Level V

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Abstract

Health benefits of aerobic exercise are indisputable and are closely related to the maintenance of mitochondrial energy homeostasis and insulin sensitivity. Flockhart et al. (2021) demonstrate, however, that a high volume of high-intensity aerobic exercise adversely affects mitochondrial function and may cause impaired glucose tolerance.

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