GSpace: an exact coalescence simulator of recombining genomes under isolation by distance.
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- Record sourced from PubMed, PMID 33964130.
- Also identified by DOI 10.1093/bioinformatics/btab261.
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Abstract
Simulation-based inference can bypass the limitations of statistical methods based on analytical approximations, but software allowing simulation of structured population genetic data without the classical n-coalescent approximations (such as those following from assuming large population size) are scarce or slow. We present GSpace, a simulator for genomic data, based on a generation-by-generation coalescence algorithm taking into account small population size, recombination and isolation by distance. Freely available at site web INRAe (http://www1.montpellier.inra.fr/CBGP/software/gspace/download.html).