New Horizon: Exercise and a Focus on Tissue-Brain Crosstalk.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 33982072.
- Also identified by DOI 10.1210/clinem/dgab333.
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Abstract
The world population is aging, leading to increased rates of neurodegenerative disorders. Exercise has countless health benefits and has consistently been shown to improve brain health and cognitive function. The purpose of this review is to provide an overview of exercise-induced adaptations in the brain with a focus on crosstalk between peripheral tissues and the brain. We highlight recent investigations into exercise-induced circulating factors, or exerkines, including irisin, cathepsin B, GPLD1, and ketones and the mechanisms mediating their effects in the brain.
Medical subject headings
- Adaptation, Physiological
- Brain
- Exercise