Diversity in immunogenomics: the value and the challenge.
Level V
Where this comes from
- Record sourced from PubMed, PMID 34002093.
- Also identified by DOI 10.1038/s41592-021-01169-5 and PMC identifier 8842483.
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Abstract
Immunogenomics studies have been largely limited to individuals of European ancestry, restricting the ability to identify variation in human adaptive immune responses across populations. Inclusion of a greater diversity of individuals in immunogenomics studies will substantially enhance our understanding of human immunology.
Medical subject headings
- B-Lymphocytes
- B-Lymphocytes/immunology
- Databases, Genetic
- Genomics
- Germ Cells
- Humans
- Immunogenetics
- Receptors, Antigen, B-Cell
- Receptors, Antigen, B-Cell/genetics
- Receptors, Antigen, B-Cell/immunology
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell/genetics
- Receptors, Antigen, T-Cell/immunology
- T-Lymphocytes
- T-Lymphocytes/immunology
- Whole Genome Sequencing