Gut Resistome of Preschool Children After Prolonged Mass Azithromycin Distribution: A Cluster-randomized Trial.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 34037753.
- Also identified by DOI 10.1093/cid/ciab485 and PMC identifier 8492121.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We evaluated the gut resistome of children from communities treated with 10 twice-yearly azithromycin distributions. Although the macrolide resistance remained higher in the azithromycin arm, the selection of non-macrolide resistance observed at earlier time points did not persist. Longitudinal resistance monitoring should be a critical component of mass distribution programs. NCT02047981.
Medical subject headings
- Anti-Bacterial Agents
- Azithromycin