Creatine promotes metastatic dissemination.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34077711.
- Also identified by DOI 10.1016/j.cmet.2021.05.012.
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Abstract
The molecular regulation of cancer metastasis is not fully understood. In this issue of Cell Metabolism, Zhang et al. (2021) discover that creatine promotes cancer metastasis in mice by promoting activation of the MPS1-Smad2/3 axis.
Medical subject headings
- Animals
- Creatine
- Mice
- Neoplasms