The treasure inside human naive pluripotency, generation of trophectoderm and blastoids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34087157.
- Also identified by DOI 10.1016/j.stem.2021.05.010.
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Abstract
Recent advances in human naive pluripotent stem cell culture have demonstrated their ability to generate trophectoderm and descendant trophoblast cell types. Moreover, the same cells when cultured in three-dimensional configurations self-organize to generate blastocyst-like structures called blastoids. These discoveries represent a major step forward in modeling early human embryonic development.
Medical subject headings
- Pluripotent Stem Cells
- Trophoblasts