Pancreatic plasticity: Unlocking exocrine lineage specification.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34087158.
- Also identified by DOI 10.1016/j.stem.2021.05.006.
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Abstract
In this issue of Cell Stem Cell, Huang et al. (2021) and Breunig et al. (2021) developed human stem-cell-derived organoid culture systems to recapitulate pancreatic acinar and ductal lineages. This provides opportunities to study cellular plasticity and transformation in pancreatic cancer initiation and progression.
Medical subject headings
- Pancreas, Exocrine
- Pancreatic Neoplasms
- Pluripotent Stem Cells