Sweet Dre-ams about intersectional genetics.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34087159.
- Also identified by DOI 10.1016/j.stem.2021.05.005.
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Abstract
Specific cell targeting with one site-specific recombinase is challenging. In this issue of Cell Stem Cell, Han et al. (2021) released a collection of Dre drivers and demonstrate how two recombinases can be combined to improve the cell specificity of lineage tracing and gene inactivation in mice.
Medical subject headings
- Integrases
- Recombinases