Increased Household Secondary Attacks Rates With Variant of Concern Severe Acute Respiratory Syndrome Coronavirus 2 Index Cases.

Buchan, Sarah A; Tibebu, Semra; Daneman, Nick; Whelan, Michael; Vanniyasingam, Thuva; Murti, Michelle; Brown, Kevin A · Clin Infect Dis · 2022

retrospective_cohort · Level III

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Abstract

We compared secondary attack rates in households with B.1.1.7 variant of concern (VOC) versus non-VOC index cases in a matched cohort in Ontario, Canada. The secondary attack rate for VOC index cases was 1.31 times higher than non-VOC index cases. This increase was particularly accentuated for asymptomatic or presymptomatic index cases.

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