The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 34117878.
- Also identified by DOI 10.1093/cid/ciab543 and PMC identifier 8906702.
- Licence recorded as CC BY-NC-ND.
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Abstract
Little is known about severe acute respiratory syndrome coronavirus 2 "vaccine-breakthrough" infections (VBIs). Here we characterize 24 VBIs in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 × 103 plaque-forming units/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains.
Medical subject headings
- COVID-19
- SARS-CoV-2