Remote firing propagation in the neural network of C. elegans.

Abstract

Understanding the mechanisms of firing propagation in brain networks has been a long-standing problem in the fields of nonlinear dynamics and network science. In general, it is believed that a specific firing in a brain network may be gradually propagated from a source node to its neighbors and then to the neighbors' neighbors and so on. Here, we explore firing propagation in the neural network of Caenorhabditis elegans and surprisingly find an abnormal phenomenon, i.e., remote firing propagation between two distant and indirectly connected nodes with the intermediate nodes being inactivated. This finding is robust to source nodes but depends on the topology of network such as the unidirectional couplings and heterogeneity of network. Further, a brief theoretical analysis is provided to explain its mechanism and a principle for remote firing propagation is figured out. This finding provides insights for us to understand how those cognitive subnetworks emerge in a brain network.