Current Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 34140459.
- Also identified by DOI 10.14309/ajg.0000000000001350 and PMC identifier 8410642.
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Abstract
The impact of the 2019 US Food and Drug Administration safety alert involving transmission of multidrug resistant organisms through fecal microbiota transplantation (FMT), and the COVID-19 pandemic on the use of FMT in children, is unknown. A survey of pediatric gastroenterologists performing FMT for Clostridioides difficile infection was conducted. Of 36 respondents, 17 (47%) and 30 (83%) changed their FMT practices related to the US Food and Drug Administration safety alert and COVID-19 pandemic, respectively, with 22 (61%) of programs halted. The US Food and Drug Administration safety alert and COVID-19 pandemic have substantially influenced the availability and access of FMT for children.
Medical subject headings
- COVID-19
- Clostridium Infections
- Fecal Microbiota Transplantation
- Practice Patterns, Physicians'
- SARS-CoV-2