Personal regulome navigation of cancer.
Where this comes from
- Record sourced from PubMed, PMID 34172966.
- Also identified by DOI 10.1038/s41568-021-00381-x and PMC identifier 9169632.
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Abstract
A systematic approach to understanding the noncoding genome in cancer promises to improve cancer diagnosis and therapy. Tracking the landscape of gene control in individual patients and single cells yields many insights for inherited and somatic mutations in cancer, extrachromosomal oncogene amplifications, and cancer immunotherapy. New technologies and bold therapeutic approaches are paving the way to truly envisage personalized cancer medicine in the future.
Medical subject headings
- Neoplasms
- Precision Medicine