Tribological, cytotoxicity and antibacterial properties of graphene oxide/carbon fibers/polyetheretherketone composite coatings on Ti-6Al-4V alloy as orthopedic/dental implants.
basic_science · Level V
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- Record sourced from PubMed, PMID 34229171.
- Also identified by DOI 10.1016/j.jmbbm.2021.104659.
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Abstract
In this work, graphene oxide/carbon fibers/polyetheretherketone (GO/CF/PEEK) composite coatings on Ti-6Al-4V (TC4) alloy were fabricated by electrostatic powder spraying method. The coatings with 0.02 wt% GO and 25 wt% CF were made to improve the wear resistance, cytocompatibility and antibacterial properties of the TC4 as orthopedic/dental implants. The physicochemical properties involving coating thickness, Vickers hardness, micromorphology, phase structures and contact angles were investigated. The results indicated that the GO/CF/PEEK coatings can significantly decrease the coefficient of friction (COF) (from 0.433 ± 0.017 to 0.085 ± 0.008) and enhance the wear resistance of TC4 alloy during the wet friction process in sliding contact with a Si<sub>3</sub>N<sub>4</sub> ball. The results showed that few scratches appeared on the GO/CF/PEEK coating. As the in vitro cytotoxicity test by murine fibroblast L929 cells shown, the GO/CF/PEEK coating revealed good cytocompatibility. More importantly, GO/CF/PEEK coating exhibited excellent suppression toward Staphylococcus aureus (S. aureus) owing to the antibacterial nature of GO. Therefore, the GO/CF/PEEK composite coated TC4 could be considered as a prospective orthopedic/dental implant material for bone tissue engineering.
Medical subject headings
- Dental Implants