<sup>18</sup>F-6-Fluoro-l-Dopa PET/CT Imaging of Congenital Hyperinsulinism.
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- Record sourced from PubMed, PMID 34230074.
- Also identified by DOI 10.2967/jnumed.120.246033.
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Abstract
Congenital hyperinsulinism is characterized by persistent hypoglycemia due to inappropriate excess secretion of insulin resulting in hyperinsulinemic hypoglycemia. The clinical course varies from mild to severe, with a significant risk for brain damage. Imaging plays a valuable role in the care of infants and children with severe hypoglycemia unresponsive to medical therapy. <sup>18</sup>F-6-fluoro-l-dopa PET/CT is the method of choice for the detection and localization of a focal lesion of hyperinsulinism. Surgical resection of a focal lesion can lead to a cure with limited pancreatectomy. This article reviews the role of <sup>18</sup>F-6-fluoro-l-dopa PET/CT in the management of this vulnerable population.
Medical subject headings
- Congenital Hyperinsulinism
- Dihydroxyphenylalanine
- Positron Emission Tomography Computed Tomography