Fused filament fabrication 3D printed polylactic acid electroosmotic pumps.

Wu, Liang; Beirne, Stephen; Cabot, Joan Marc; Paull, Brett; Wallace, Gordon G; Innis, Peter C · Lab Chip · 2021

basic_science · Level V

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Abstract

Additive manufacturing (3D printing) offers a flexible approach for the production of bespoke microfluidic structures such as the electroosmotic pump. Here a readily accessible fused filament fabrication (FFF) 3D printing technique has been employed for the first time to produce microcapillary structures using low cost thermoplastics in a scalable electroosmotic pump application. Capillary structures were formed using a negative space 3D printing approach to deposit longitudinal filament arrangements with polylactic acid (PLA) in either "face-centre cubic" or "body-centre cubic" arrangements, where the voids deliberately formed within the deposited structure act as functional micro-capillaries. These 3D printed capillary structures were shown to be capable of functioning as a simple electroosmotic pump (EOP), where the maximum flow rate of a single capillary EOP was up to 1.0 μl min<sup>-1</sup> at electric fields of up to 750 V cm<sup>-1</sup>. Importantly, higher flow rates were readily achieved by printing parallel multiplexed capillary arrays.

Medical subject headings