The impact of preoperative motor weakness on postoperative opioid use after ACDF.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 34276147.
- Also identified by DOI 10.1016/j.jor.2021.06.003 and PMC identifier 8267480.
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Abstract
This study aims to determine if preoperative weakness is an isolated risk factor for prolonged postoperative opioid use after anterior cervical discectomy and fusion (ACDF). Patients with preoperative weakness were significantly more likely to have prolonged and inappropriate opioid use and have a single prescription mean morphine equivalent (MME) ≥ 200. Logistic regression isolated preoperative weakness, opioid tolerance, depression, and VAS Neck pain as independent predictors of extended opioid use. High postoperative opioid dose (MME ≥ 90) correlated with opioid tolerance, younger age, male sex, greater CCI, prior cervical surgery, and preoperative VAS Neck pain on regression.