Sex, drugs, and anaesthesia research.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34330415.
- Also identified by DOI 10.1016/j.bja.2021.06.025.
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Abstract
In this issue of the British Journal of Anaesthesia, Joksimovic and colleagues report significant sex differences in sensitivity to the behavioural and neurophysiological effects of 3β-OH, a novel neurosteroid anesthetic. Female rats were more sensitive to the effects of 3β-OH than male rats, although the mechanims remain unclear. Sex differences have been understudied in anaesthesia research, and this article by Joksimovic and colleagues emphasizes the need to devote more effort to understanding these differences.
Medical subject headings
- Anesthesia
- Anesthetics
- Pharmaceutical Preparations