Magneto-Endosomalytic Therapy for Cancer.

Zhao, Pengfei; Han, Yan; Nguyen, Holly; Corey, Eva; Gao, Xiaohu · Adv Healthc Mater · 2022

basic_science · Level V

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Abstract

A remarkably simple yet effective mode of cancer treatment is reported by repurposing clinically approved magnetic nanoparticles (MNPs). Intracellular nanoparticle self-assembly directed by static parallel magnetic fields leads to cell death in targeted tissues while leaving other cells and organs intact. This simple concept opens a new avenue to treat cancer, capitalizing on nanosciences and the nanoparticle (NP) design principles accumulated in the past decades.

Medical subject headings