Know thy neighbor: Modeling spatiotemporal cell-fate patterns in a neural stem cell niche.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34358437.
- Also identified by DOI 10.1016/j.stem.2021.07.005.
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Abstract
How lineage and the microenvironment influence stem cell homeostasis at a population level remains unresolved. In this issue of Cell Stem Cell, Dray et al. (2021) use in vivo imaging and statistical modeling to discover a key role for local progenitor cell descendants in constraining neural stem cell divisions.
Medical subject headings
- Neural Stem Cells
- Stem Cell Niche