First come, first served: Mammalian recombination is timed to replication.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34358467.
- Also identified by DOI 10.1016/j.cell.2021.07.014.
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Abstract
Meiotic recombination drives the formation of new chromosomes in germ cells and is essential for fertility in mammals. In this issue of Cell, Pratto et al. have developed a method to map replication origins directly in mammalian tissue for the first time, revealing evolutionary conservation between replication timing and meiotic recombination in males.
Medical subject headings
- Mammals
- Meiosis