Purple sulfur bacteria fix N<sub>2</sub> via molybdenum-nitrogenase in a low molybdenum Proterozoic ocean analogue.

Philippi, Miriam; Kitzinger, Katharina; Berg, Jasmine S; Tschitschko, Bernhard; Kidane, Abiel T; Littmann, Sten; Marchant, Hannah K; Storelli, Nicola et al. · Nat Commun · 2021

basic_science · Level V

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Abstract

Biological N<sub>2</sub> fixation was key to the expansion of life on early Earth. The N<sub>2</sub>-fixing microorganisms and the nitrogenase type used in the Proterozoic are unknown, although it has been proposed that the canonical molybdenum-nitrogenase was not used due to low molybdenum availability. We investigate N<sub>2</sub> fixation in Lake Cadagno, an analogue system to the sulfidic Proterozoic continental margins, using a combination of biogeochemical, molecular and single cell techniques. In Lake Cadagno, purple sulfur bacteria (PSB) are responsible for high N<sub>2</sub> fixation rates, to our knowledge providing the first direct evidence for PSB in situ N<sub>2</sub> fixation. Surprisingly, no alternative nitrogenases are detectable, and N<sub>2</sub> fixation is exclusively catalyzed by molybdenum-nitrogenase. Our results show that molybdenum-nitrogenase is functional at low molybdenum conditions in situ and that in contrast to previous beliefs, PSB may have driven N<sub>2</sub> fixation in the Proterozoic ocean.

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