Going with the Flow: The Promise of Plasma-Only Circulating Tumor DNA Assays.

Bent, Alisha; Kopetz, Scott · Clin Cancer Res · 2021

editorial · Level V

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Abstract

Circulating tumor DNA (ctDNA) has emerged as a noninvasive diagnostic and prognostic tool for colorectal cancer. Here, we discuss studies that evaluate the ability of plasma-only ctDNA assays to detect minimal residual disease and the potential benefit of integration of methylation into ctDNA assays.<i>See related articles by Parikh et al., p. 5586 and Taieb et al., p. 5638</i>.

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