18F-PSMA-1007 Uptake in Paget Disease of the Bone: An "Iron Man" Sign.
case_report · Level V
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- Record sourced from PubMed, PMID 34392292.
- Also identified by DOI 10.1097/RLU.0000000000003867.
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Abstract
18F-PSMA is a promising tracer for both staging and detection of biochemical recurrence in prostate cancer. PSMA is also expressed in the benign pathological conditions. We report a case of 81-year-old man with a known case of prostate cancer who underwent 18F-PSMA for restaging. 18F-PSMA PET/CT shows intense tracer uptake in the frontal bone appearing like an "Iron Man" sign. Corresponding noncontrast CT images, pagetoid changes with thickened cortex, mixed lytic/sclerotic mottled pattern. It is important to recognize 18F-PSMA expression in the benign nonprostatic pathologies to avoid false interpretation.
Medical subject headings
- Niacinamide
- Oligopeptides
- Osteitis Deformans
- Positron Emission Tomography Computed Tomography