Increased 68Ga-FAPI Uptake in the Pulmonary Cryptococcus and the Postradiotherapy Inflammation.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 34406184.
- Also identified by DOI 10.1097/RLU.0000000000003873.
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Abstract
A 51-year-old man, previously treated for nasopharyngeal carcinoma, presented a newly detected pulmonary nodule. This patient underwent 18F-FDG and 68Ga-FAPI PET/CT to detect tumor recurrence under the prospective study NCT04416165. Both 18F-FDG and 68Ga-FAPI PET/CT showed intense uptake in a pulmonary nodule in the right lower lobe. In addition, 68Ga-FAPI PET/CT demonstrated increased uptake in the nasopharynx that previously treated with radiotherapy. The pulmonary nodule was found to be cryptococcus by the CT-guided biopsy, and the increased 68Ga-FAPI uptake in the nasopharynx was interpreted as false-positive finding due to a stable Epstein-Barr virus level and no progression on follow-up imaging.
Medical subject headings
- Cryptococcus
- Epstein-Barr Virus Infections
- Nasopharyngeal Neoplasms