ksrates: positioning whole-genome duplications relative to speciation events in KS distributions.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34406368.
- Also identified by DOI 10.1093/bioinformatics/btab602.
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Abstract
We present ksrates, a user-friendly command-line tool to position ancient whole-genome duplication events with respect to speciation events in a phylogeny by comparing paralog and ortholog KS distributions derived from genomic or transcriptomic sequences, while adjusting for substitution rate differences among the lineages involved. ksrates is implemented in Python 3 and as a Nextflow pipeline. The source code, Singularity and Docker containers, documentation and tutorial are available via https://github.com/VIB-PSB/ksrates. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Gene Duplication
- Genome