Importance of bone turnover for therapeutic decisions in patients with CKD-MBD.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34420656.
- Also identified by DOI 10.1016/j.kint.2021.05.024.
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Abstract
Patients with chronic kidney disease-mineral and bone disorder (CKD-MBD) frequently have low bone formation rates. A recent review suggested that adynamic bone disease is not always associated with negative outcomes and therefore antiresorptive medications could be used more often. However, there is currently no evidence to support an improvement in fracture risk or mortality in patients with CKD-MBD and low bone turnover who are treated with antiresorptive medication. There is reasonable pathophysiological evidence suggesting that it may even be harmful.
Medical subject headings
- Bone Density Conservation Agents
- Bone Diseases
- Chronic Kidney Disease-Mineral and Bone Disorder