Variability in Oral Desmopressin Dose Requirements in Children with Central Diabetes Insipidus.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 34487771.
- Also identified by DOI 10.1016/j.jpeds.2021.08.087.
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Abstract
There is inconsistency in the amount of oral desmopressin that children with central diabetes insipidus require. We investigated whether clinical characteristics influenced desmopressin dose requirements in 100 children with central diabetes insipidus. Extremely large doses were associated with acquired etiology (P = .04), greater body mass index z score, intact thirst, and additional pituitary hormone deficiencies (P < .001).
Medical subject headings
- Antidiuretic Agents
- Deamino Arginine Vasopressin
- Diabetes Insipidus, Neurogenic