Microglia have a grip on brain microvasculature.
Where this comes from
- Record sourced from PubMed, PMID 34489417.
- Also identified by DOI 10.1038/s41467-021-25595-3 and PMC identifier 8421408.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Microglia are brain resident immune cells with multiple functions. However, little is known about microglia-vascular interactions. In a recent paper published in Nature Communications, Bisht et al. identify a signalling mechanism that attracts and maintains microglia at the capillary wall. Moreover, they show that microglia regulate capillary vascular tone, playing a more significant role in blood flow regulation than previously thought.
Medical subject headings
- Brain
- Microglia