False Coronavirus Disease 2019 Cases due to Contamination by Inactivated Virus Vaccine.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 34498683.
- Also identified by DOI 10.1093/cid/ciab684 and PMC identifier 8499976.
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Abstract
A false-positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse-transcription polymerase chain reaction result can lead to unnecessary public health measures. We report 2 individuals whose respiratory specimens were contaminated by an inactivated SARS-CoV-2 vaccine strain (CoronaVac), likely at vaccination premises. Incidentally, whole genome sequencing of CoronaVac showed adaptive deletions on the spike protein, which do not result in observable changes of antigenicity.
Medical subject headings
- COVID-19
- COVID-19 Vaccines