68Ga-FAPI-04 PET/CT Imaging for Fibrous Dysplasia of the Bone.

Wang, Yingwei; Wu, Junhao; Liu, Lin; Peng, DengSai; Chen, Yue · Clin Nucl Med · 2022

case_report · Level V

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Abstract

68Ga-labeled quinoline-based fibroblast activation protein inhibitors (68Ga-FAPIs) are promising agents for tumor imaging. However, some nonneoplastic lesions can also cause increased FAPI uptake. We report a case of a patient with polyostotic fibrous dysplasia who showed widespread and intense metabolic activity on 68Ga-FAPI PET/CT. Physicians should be aware that fibrous dysplasia can also cause elevated FAPI activity.

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