Comment on "Aberrant type 1 immunity drives susceptibility to mucosal fungal infections".
editorial · Level V
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- Record sourced from PubMed, PMID 34529464.
- Also identified by DOI 10.1126/science.abi5459 and PMC identifier 8509635.
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Abstract
Break <i>et al</i>. (Research Articles, 15 January 2021, eaay5731) suggest that chronic mucocutaneous candidiasis in humans with inborn errors of <i>AIRE</i> and autoimmune polyendocrine syndrome type 1 is due to excessive interferon-γ production and not to autoantibodies neutralizing interleukin-17 cytokines. We argue that both claims are not conclusively supported by their data and are at odds with 35 years of study.
Medical subject headings
- Mycoses