Breaking down walls in prostate cancer with the MURAL collection of patient-derived xenografts.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34535657.
- Also identified by DOI 10.1038/s41467-021-25783-1 and PMC identifier 8448875.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A bank of 59 well-characterised prostate cancer patient-derived xenografts was established, including 17 classed as research-ready covering the disease-spectrum which, plus associated resources (organoids, serum, DNA/RNA profiles, tissue), are available for collaborative projects. This eagerly-anticipated resource will facilitate pre-clinical prostate cancer therapy studies.
Medical subject headings
- Prostatic Neoplasms
- Xenograft Model Antitumor Assays