Critical Needs in Advancing Shigella Vaccines for Global Health.

MacLennan, Calman A; Talaat, Kawsar R; Kaminski, Robert W; Cohen, Dani; Riddle, Mark S; Giersing, Birgitte K · J Infect Dis · 2022

expert_opinion · Level V

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Abstract

Advancing new O-antigen-based <i>Shigella</i> vaccines is critically dependent on development of an international standard serum and harmonized ELISA, demonstration of field efficacy in young children in low- and middle-income countries, and early engagement with regulators and policy makers.

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