Closing the Rift: Discovery of a novel virus receptor.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34559984.
- Also identified by DOI 10.1016/j.cell.2021.09.004.
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Abstract
In this issue of Cell, Ganaie et al. reports the identification of LRP1 as a receptor of the highly pathogenic Rift Valley fever virus. By using genome-wide CRISPR-Cas9 screening and functional studies, Ganaie et al. identified LRP1 and several co-factors as essential elements for virus infection.
Medical subject headings
- Rift Valley Fever
- Rift Valley fever virus