Estrogen receptor gets a grip on RNA.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34559987.
- Also identified by DOI 10.1016/j.cell.2021.09.012.
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Abstract
The nuclear hormone receptor estrogen receptor alpha (ERα) is a well-known transcription factor present in many breast cancers, where it promotes cancer progression. In this issue of Cell, Xu et al. report that ERα is also an RNA-binding protein and that its post-transcriptional activity enables cancer cell fitness and survival.
Medical subject headings
- Breast Neoplasms
- Receptors, Estrogen