How the discovery of microbial opsins led to the development of optogenetics.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 34562360.
- Also identified by DOI 10.1016/j.cell.2021.08.022.
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Abstract
This year's Lasker Award recognizes Dieter Oesterhelt, Peter Hegemann, and Karl Deisseroth for their discovery of microbial opsins as light-activated ion conductors and the development of optogenetics using these proteins to regulate neural activity in awake, behaving animals. Optogenetics has revolutionized neuroscience and transformed our understanding of brain function.
Medical subject headings
- Bacteria
- Opsins
- Optogenetics