From microbial membrane proteins to the mysteries of emotion.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 34562367.
- Also identified by DOI 10.1016/j.cell.2021.08.018 and PMC identifier 10327439.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
On the occasion of the 2021 Lasker Basic Medical Research Award to Karl Deisseroth, Peter Hegemann, and Dieter Oesterhelt (for "the discovery of light-sensitive microbial proteins that can activate or deactivate individual brain cells-leading to the development of optogenetics and revolutionizing neuroscience"), Deisseroth reflects on this international collaboration, his basic mechanistic and structural discoveries regarding microbial channels that transduce photons into ion current, the causal exploration of brain cell function, and the pressing mysteries of psychiatry.
Medical subject headings
- Bacteria
- Bacterial Proteins
- Emotions
- Membrane Proteins