Impact of COVID-19 on Prescribing Trends of Direct-Acting Antivirals for the Treatment of Hepatitis C in Ontario, Canada.

Konstantelos, Natalia; Shakeri, Ahmad; McCormack, Daniel; Feld, Jordan J; Gomes, Tara; Tadrous, Mina · Am J Gastroenterol · 2021

cross_sectional · Level IV

Where this comes from

Abstract

Direct-acting antivirals (DAAs) are curative treatments for hepatitis C. However, initiation of these treatments requires adequate healthcare access. Coronavirus 2019 (COVID-19) resulted in restrictions to healthcare services in March 2020. We examined the impact of COVID-19 on the number of individuals dispensed DAAs. This is a cross-sectional study examining the number of individuals dispensed DAAs in Ontario, Canada, from 2018 to 2020. Time-series models determined the impact of healthcare restrictions on DAA dispensations. Healthcare restrictions resulted in a 49.3% decrease in DAA dispensations (P = 0.026). COVID-19-related healthcare restrictions significantly affected access to DAAs. Studies exploring the long-term effects on reduced treatment are needed.

Medical subject headings