Unraveling the mechanisms of IVIG immunotherapy in MIS-C.

Ganigara, Madhusudan; Sharma, Chetan; Bayry, Jagadeesh · Cell Rep Med · 2021

editorial · Level V

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Abstract

In <i>The Journal of Clinical Investigation</i>, Zhu et al.<sup>1</sup> report that intravenous immunoglobulin (IVIG) targets IL-1β<sup>+</sup> neutrophils to exert anti-inflammatory effects in multisystem inflammatory syndrome in children (MIS-C), a post-infectious inflammatory condition associated with COVID-19.

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