A new paper-based biosensor for therapeutic drug monitoring.

Lantigua, Darlin; Trimper, Jamie; Unal, Baris; Camci-Unal, Gulden · Lab Chip · 2021

basic_science · Level V

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Abstract

Tacrolimus is one of the most effective and prevalent drugs used to combat vascularized composite allotransplantation rejection. We have fabricated a rapid and easy-to-use six-layer paper based microfluidic device using the principles of competitive immunoassays and vertical flow microfluidics for colorimetric detection of tacrolimus in a small volume of blood.

Medical subject headings